The Cannabis family of plants is the host to hundreds of compounds known as cannabinoids. THC and CBD are the most well-known cannabinoids presently on the market. However, there are multiple minor cannabinoids which are proving to be beneficial for a number of reasons as well. We dive deeper into some of these below.
Cannabidiol is the major cannabinoid in hemp and it binds mostly to the CB2 receptors of the endocannabinoid system. This is the non-psychoactive major cannabinoid and one of hundreds that are in the plant family that do not cause a “high” response but do have benefits of their own. One of the most studied cannabinoids thanks to its popularity in the marketplace, it has been found to be helpful in several issues that we deal with.
Cannabigerol is a minor cannabinoid at harvest but it is a major cannabinoid compound in what it does. When they first form on the plants, all cannabinoids start as their acidic parent. CBG begins as CBG-a. The interesting and unique thing about CBG-a is that it is often referred to as the "Mother Cannabinoid" as it can develop into CBG, CBD, THC or CBC. Said to be a great helper to the major cannabinoids and their work, CBG can bind to either CB1 or CB2 receptors. Its path and possibilities are a big reason why we have formulations that are sure to add CBG to the blend since, by harvest, it is naturally in smaller numbers.
Cannabichromene is unique in that it does not bind with CB1 or CB2 but to some much more unique cannabinoid receptors in the body known as TRPV1 (the vanilloid receptor 1) and TRPA1 (transient receptor potential ankyrin 1) and when CBC activates them, it encourages the body to release more of its own endocannabinoids (compounds we make) like anandamide which is often referred to as “the bliss molecule” and is often associated with pain perception.
Cannabinol is best known to be the cannabinoid that forms as THC ages. In states that allow marijuana, many will seek out aged or older cannabis flower options to get more of this compound. In hemp, it occurs in smaller levels as well but has some great assistive properties. When coupled with CBD, it works alongside it within the entourage effect, powering up the relaxing power of CBD. While some believed it to do so on its own, it was recently found that it only does this when paired with its major cannabinoid partner.
The latest in talked-about cannabinoid compounds is Delta-8 THC. While like its sibling Delta-9 in many ways, it also has some important key differences. Delta-8 is said to have many of the same benefits that Delta-9 THC carries, and it binds to the CB1 receptors like its sibling does, but it is reported to have around half the psychotropic response that Delta-9 has. A few atomic bond differences separate the two and, since Delta-8 can be made from CBD, it is being found in greater abundance in the marketplace. Be aware, however, consumer reporting has Delta-8 as often having a greater response than CBD in areas of relaxation and new consumers are advised to start with a small amount and not be driving or operating machinery while enjoying Delta-8 products.